Whole Exome Sequencing

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Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Choose efficient, cost-effective sequencing focused on protein-coding regions. Our whole exome sequencing (WES) service lets you choose from a range of industry-leading library prep kits for hybridization enrichment – including those from Agilent and Twist – to make sure you get the reliable libraries you need.

Whole Exome Sequencing

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Create an account on our ordering platform and submit orders right from your lab chair.

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Whole exome sequencing (WES) is a targeted approach that makes it possible to identify variations in the protein-coding part of a genome. In humans, only around 1% of the genome consists of exomes. However, most disease-related genetic variants occur in exons, making these regions crucial to many genetic studies.

Because the sequenced region is narrowed down from gigabasepairs to megabasepairs, sequencing throughput required per sample per analysis is much smaller. This makes exome sequencing unbeatable in terms of precision and economy and method of choice for many researchers and clinicians.

applications

WES can provide insights into the genetic origins of Mendelian diseases or traits that are hard to study with conventional gene discovery strategies. Exome sequencing of parent–child trios is also a highly effective approach for identifying de novo coding mutations of a disease, as it is very unlikely that multiple de novo events occur in one specific gene.

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Looking for more library kits? Ready to run samples?

You can have a look to the list of all library kits available and the Macrogen Europe sample criteria. RTR samples? You can also find the library criteria in case your sample are ready for sequencing.

Library Kits

Our partnership with TWIST and Agilent allows us to offer you the best library kits for Whole Exome Sequencing. Here you can find our top selling library kits, their specifications and some useful information to prepare your sample

We advise sending samples in a volume ranging from 25 to 50 μl to prevent them from drying out during shipment

For TWIST, a minimum 50ng is required for input. However, Macrogen Europe recommends to send 200ng for optiomal results

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Looking for more library kits? Ready to run samples?

You can have a look to the list of all library kits available and the Macrogen Europe sample criteria. RTR samples? You can also find the library criteria in case your sample are ready for sequencing.

Sequencers

  • Illumina
  • NovaSeq X
  • NovaSeq 6000
  • NextSeq

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Looking for more library kits? Ready to run samples?

You can have a look to the list of all library kits available and the Macrogen Europe sample criteria. RTR samples? You can also find the library criteria in case your sample are ready for sequencing.

Yes, we have bioinformatics in-house

Knowing the purpose of your research is essential to establish the correct sequencing configuration and statistic analysis. Let us know what is the objective of your research and we will guide you in getting the correct bioinformatics services.

From raw data to customized services

For most researchers obtaining RAW data is sufficient for their research. However, Macrogen Europe is ready to provide bioinformatic analysis for your project.

Have a look at the top-selling standard and advanced bioinformatics reports for Whole Exome Sequencing.

Family analysis

somatic analysis

Other bioinformatics services

The Advanced Bioinformatics services listed above are not available for custom target sequencing. Please, contact our team about extra BI services

Yes, we have bioinformatics in-house

Knowing the purpose of your research is essential to establish the correct sequencing configuration and statistic analysis. Let us know what is the objective of your research and we will guide you in getting the correct bioinformatics services.