Whole Genome Sequencing

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

What is mappable coverage? What coverage do you need?

Understanding next-generation-sequencing can be challenging. Knowing how much data your project needs is essential. Read and learn with Macrogen Europe.

Do you need to sequence the complete genomic information of your samples? Macrogen Europe’s fast, high-quality WGS services provide the most comprehensive tool for detecting genetic abnormalities such as single nucleotide polymorphisms (SNPs), indels, copy number variation (CNV) and structural variants (SVs).

Whole Genome Sequencing

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Create an account on our ordering platform and submit orders right from your lab chair.

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

What is mappable coverage? What coverage do you need?

Understanding next-generation-sequencing can be challenging. Knowing how much data your project needs is essential. Read and learn with Macrogen Europe.

WGS analyses an organism’s entire genome, as opposed to whole exome sequencing and targeted sequencing, which studies specific areas. A single test identifies all variations in the genome such as single-nucleotide variants, insertion, deletion, copy number variants, and translocations. This approach covers both the coding and non-coding parts of the genome. For this reason, WGS is the sequencing option of choice to study factors that affect the entire genome and to analyze noncoding DNA.

Emerging technologies provide the better resolution of challenging regions containing highly variable and repetitive elements, supported by a readily available long-read sequencing platform and proficient library preparation kit selection from Macrogen, thereby speeding the adoption of this testing into routines.

Applications

This is particularly beneficial when unexplained conditions are to be discovered in vital genetic diagnosis and treatment. WGS is essential in a wide range of scientific fields, both fundamental and applied. It can identify genetic variations across the genome, which is why it is commonly used in agriculture and evolutionary biology and in clinical and pharmaceutical applications such as infectious diseases, immunology, cancer research, various inherited conditions and drug development.

Short-read vs long-read sequencing

Combine short-read and long-read sequencing to fill gaps or correct errors during genome assembly

De Novo sequencing vs resequencing

De novo sequencing offers a way to uncover genome information about microorganisms, animals and plants when no reference genome is available. The analysis works by assembling long parallel phases of genetic material without referencing an existing nucleotide sequence. This type of WGS is highly accurate and can replicate or complete a blueprint for complex or polyploid genomes.

Resequencing a genome involves comparing newly sequenced DNA to a previously created reference genome. It is a highly efficient, fast and cost-effective way of analyzing the genomes of commonly studied organisms. Whole genome resequencing can scan or test for specific genetic variations. Any differences between the sample DNA and the reference could be an indication of a new variant or a potential disorder in a clinical setting.

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

What is mappable coverage? What coverage do you need?

Understanding next-generation-sequencing can be challenging. Knowing how much data your project needs is essential. Read and learn with Macrogen Europe.

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Looking for more library kits? Ready to run samples?

You can have a look to the list of all library kits available and the Macrogen Europe sample criteria. RTR samples? You can also find the library criteria in case your sample are ready for sequencing.

Library kits and Sequencers

We have a partnership with different suppliers, such as Illumina, Watchmaker, PacBio and Oxford Nanopore, that allows us to have a huge variety of library preparation kits and sequencing power for you. Have a look at our top-selling service and the requirements to submit your samples for each application.

The kits mentioned below are the most frequently used. For more kits please, contact our team. We advise sending samples in a volume ranging from 25 to 50 μl to prevent them from drying out during shipment

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Looking for more library kits? Ready to run samples?

You can have a look to the list of all library kits available and the Macrogen Europe sample criteria. RTR samples? You can also find the library criteria in case your sample are ready for sequencing.

Sequencers

  • Illumina
  • NovaSeq X
  • NovaSeq 6000
  • NextSeq
  • MiSeq
  • PacBio
  • Revio
  • PacBio Sequel IIe
  • Oxford Nanopore
  • PromethION

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you

Book your free consultation

Now, if you like what you read or you have any extra questions, you can book a free online meeting to discuss your project with our consultants. Tell us about your project and we will get the correct consultant for you.

Looking for more library kits? Ready to run samples?

You can have a look to the list of all library kits available and the Macrogen Europe sample criteria. RTR samples? You can also find the library criteria in case your sample are ready for sequencing.

Yes, we have bioinformatics in-house

Knowing the purpose of your research is essential to establish the correct sequencing configuration and statistic analysis. Let us know what is the objective of your research and we will guide you in getting the correct bioinformatics services.

From Raw Data to Customized services

For most researches obtaining RAW data is sufficient for their research. However, Macrogen Europe is ready to provide bioinformatic analysis for your project.

Mapping and Annotation

Variant Identification

De Novo Assembly and Annotation

other bioinformatic services

Macrogen Europe’s analysis is not limited to the services listed above. The visualization, pangenome analysis, and the other analysis are serviced upon the dsicussion.

Yes, we have bioinformatics in-house

Knowing the purpose of your research is essential to establish the correct sequencing configuration and statistic analysis. Let us know what is the objective of your research and we will guide you in getting the correct bioinformatics services.